HEALTH
COVID-19 – Pfizer to apply for authorization for a third dose of vaccine
Trials are already underway for a third dose of Covid-19 vaccine, administered six months after the second, to increase the level of neutralizing antibodies. The possibility of a third dose of Covid-19 vaccine is beginning to materialize. The Pfizer/BioNTech alliance plans to apply for authorisation in the coming weeks, in the United States and Europe in particular, the companies announced in a statement. This booster dose is intended to provide enhanced immune protection to those already vaccinated with the first two doses.
“Pfizer and BioNTech have seen encouraging results from ongoing trials for a third dose of the current vaccine,” they explained. They “plan to submit this data to the FDA, EMA and other regulatory authorities in the coming weeks,” they added in reference to the US and European Medicines Agencies.“Preliminary study data show that a booster dose given six months after the second dose has a consistent tolerance profile, while generating high levels of neutralizing antibodies” against the virus, including the Beta variant, appeared in South Africa. These levels are “five to ten times higher” than those observed after the two initial doses.
We have seen encouraging #clinicaltrial data in a small number of participants in our study examining a third dose of the current Pfizer-BioNTech #COVID19 vaccine, BNT162b2. pic.twitter.com/6sae05FKEe
— Pfizer Inc. (@pfizer) July 8, 2021
Decline in efficiency expected
The two companies also pointed out that their vaccine had shown good laboratory results against the Delta variant, and that a third dose would therefore be able to boost immunity against it as well. Tests are underway to “confirm this hypothesis,” they said. The results of this study will be published in a scientific journal.
“Although protection against severe cases of the disease remains high for six months, a decline in its effectiveness against symptomatic cases over time and the emergence of variants is expected,” the statement said. “That’s why we said, and we continue to believe, that it is likely, based on the totality of the data we have now, that a third dose may be required between 6 and 12 months after vaccination,” he added.
The U.S. drug agency, the FDA, and the lead federal public health agency, the Centers for Disease Prevention and Control, issued a joint statement on Thursday night that said they are studying “the need for a recall or not”.“Americans who have been fully vaccinated do not need a recall at this time,” the two health authorities say. “We are prepared to administer booster doses if and when science has shown that they are needed,” they added.
In France, the Prime Minister has already taken a position on the most vulnerable.On his way to Blois on Thursday, he explained that for these people, “who were vaccinated first both because they are vulnerable and this vaccination was done early,” a “third dose” would be needed.
Source : Le Parisien
HEALTH
COVID 19 – A new variant we discovered
According to a senior official at the World Health Organization, a new highly mutated variant of COVID called BA.2.86 has been discovered in several countries including Switzerland, South Africa, as well as Israel, Denmark, the United States and the United Kingdom.
According to “Reuters”, the variant was first spotted in Denmark on 24 July after sequencing of the virus infecting a patient at risk of becoming seriously ill”. And so it was detected “in other symptomatic patients, during routine checks at airports and in wastewater samples in a handful of countries”.
Thus, scientists have indicated that “although it was important to monitor BA.2.86, it was unlikely to cause a devastating wave of serious illness and death given the immune defenses developed worldwide as a result of vaccination and previous infection”.
WHO COVID-19 technical officer Maria Van Kerkhove said, “The numbers are still low”. But the reduction in global surveillance could lead to rapid circulation of the virus…
HEALTH
TOBACCO CONTROL: Seven out of 10 people protected by anti-smoking measures
A new report from the World Health Organization (WHO) highlights that 5.6 billion people, or 71% of the world’s population, are now protected by at least one good practice policy to save lives from deadly smoking, five times more than in 2007.
Over the past 15 years, since WHO’s MPOWER measures were introduced globally, smoking rates have fallen. Without this reduction, the UN World Health Agency estimates that there are now 300 million more smokers worldwide. This new WHO report on the global tobacco epidemic focuses on protecting the public from passive smoking, noting that nearly 40% of countries now have fully non-smoking indoor public places. The report assesses the progress made by countries in tobacco control and shows that two other countries, Mauritius and the Netherlands, have reached the level of best practices for all MPOWER measures, a feat that only Brazil and Turkey have achieved so far. These data show that, slowly but surely, more and more people are protected from the harms of tobacco by WHO policies based on evidence and best practices.”said Dr Tedros Adhanom Ghebreyesus, Director-General of WHO, congratulating Mauritius on becoming the first country in Africa and the Netherlands on becoming the first country in the European Union to implement WHO’s comprehensive tobacco control policies at the highest level. Eight countries are only one policy away from joining the leaders of tobacco control: Ethiopia, Iran, Ireland, Jordan, Madagascar, Mexico, New Zealand and Spain. However, much remains to be done: 44 countries are not protected by any of WHO’s MPOWER measures. At the same time, 53 countries have still not adopted a total ban on smoking in health facilities. In addition, only half of the countries have smoke-free private workplaces and restaurants.
Passive smoking
“WHO urges all countries to implement all MPOWER measures at the level of best practices to fight the tobacco epidemic, which kills 8.7 million people worldwide, and to oppose the tobacco and nicotine industries, who are lobbying against these public health measures,” said Dr Ruediger Krech, Director of Health Promotion at WHO. About 1.3 million people die each year from second-hand smoke. All of these deaths could be prevented. People exposed to second-hand smoke are at risk of dying from heart disease, stroke, respiratory disease, type 2 diabetes and cancer. In this fight against tobacco, the ban on smoking in public spaces is only one of the measures of the Effective Tobacco Control Package, MPOWER, designed to help countries implement the WHO Framework Convention on Tobacco Control and stem the tobacco epidemic. The paper shows that all countries, regardless of income level, can lower the demand for deadly tobacco, achieve major public health victories and save billions of dollars in health care and production costs.
HEALTH
SENEGAL – 400 cases of measles recorded
Measles is back in force, with more than “400 cases recorded nationally”. It is a revelation of Doctor Boly Diop, responsible for epidemiological and post-vaccination surveillance at the Ministry of Health and Social Action, on Thursday, July 13, 2023.
“Performance in the first half of the year revealed the existence of a measles epidemic,” said Dr. Boly Diop, noting that Fatick is the only one of the country’s 14 regions that has yet to register a confirmed case of measles.
Outside of Fatick, all regions have confirmed cases of measles and there are districts that have become epidemic. This means that today, measles is back in force, there are confirmed cases and epidemics that are recorded throughout the regions,’ he said, on the sidelines of a quarterly coordination meeting for epidemiological surveillance.
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